|Other Names||Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial, PDPr, PDPR, KIAA1990|
|Target/Specificity||The synthetic peptide sequence is selected from aa 836-850 of HUMAN PDPR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
PDPR decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity).
Sugden, M.C., et al. Am. J. Physiol. Endocrinol. Metab. 284 (5), E855-E862 (2003) : Ohara, O., et al. DNA Res. 9(2):47-57(2002) Lawson, J.E., et al. J. Biol. Chem. 272(50):31625-31629(1997)
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