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XCR1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P46094 |
|---|---|
| Clone Names | 101008027 |
| Gene ID | 2829 |
|---|---|
| Other Names | Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1, XCR1, CCXCR1, GPR5 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | XCR1 |
|---|---|
| Synonyms | CCXCR1, GPR5 |
| Function | Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a chemokine receptorbelonging to the G protein-coupled receptor superfamily. The familymembers are characterized by the presence of 7 transmembranedomains and numerous conserved amino acids. This receptor is mostclosely related to RBS11 and the MIP1-alpha/RANTES receptor. Ittransduces a signal by increasing the intracellular calcium ionslevel. The viral macrophage inflammatory protein-II is anantagonist of this receptor and blocks signaling. Two alternativelyspliced transcript variants encoding the same protein have beenfound for this gene.
References
Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)Crozat, K., et al. J. Exp. Med. 207(6):1283-1292(2010)Bachem, A., et al. J. Exp. Med. 207(6):1273-1281(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Luttichau, H.R. Virol. J. 5, 50 (2008) :
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