|Other Names||Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L, RBPJL, RBPL, RBPSUHL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Putative transcription factor, which cooperates with EBNA2 to activate transcription.|
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Provided below are standard protocols that you may find useful for product applications.
In mouse, recombining binding protein L (RBP-L) is atranscription factor that binds to DNA sequences almost identicalto that bound by the Notch receptor signalling pathwaytranscription factor RBP-J. However, unlike RBP-J, RBP-L does notinteract with Notch receptors. RBP-L has been shown to activatetranscription in concert with Epstein-Barr virus nuclear antigen-2(EBNA2). The protein encoded by this gene is similar in sequence tothe mouse RPB-L protein and Drosophila suppressor of hairlessprotein.
Beres, T.M., et al. Mol. Cell. Biol. 26(1):117-130(2006)Deloukas, P., et al. Nature 414(6866):865-871(2001)Nakagawa, H., et al. Oncogene 19(2):210-216(2000)Tani, S., et al. J. Hum. Genet. 44(1):73-75(1999)Minoguchi, S., et al. Mol. Cell. Biol. 17(5):2679-2687(1997)
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