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SH2D4A Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H788
Clone Names 101008214
Peptide ID 101008214
Additional Information
Gene ID 63898
Other Names SH2 domain-containing protein 4A, Protein SH(2)A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH2D4A
Synonyms PPP1R38, SH2A
Function Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Cellular Location Cytoplasm. Note=Located at podocyte foot processes.
Tissue Location Ubiquitously expressed. Aberrantly expressed in some cancers.
Research Areas
Citations (0)

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Background

SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Li, T., et al. BMB Rep 42(8):516-522(2009)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Lapinski, P.E., et al. J. Immunol. 181(3):2019-2027(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 80.00
Cat# BP12049a
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