Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   FOXN1 Antibody (Center) Blocking peptide   

FOXN1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O15353
Clone Names 101109058
Peptide ID 101109058
Additional Information
Gene ID 8456
Other Names Forkhead box protein N1, Winged-helix transcription factor nude, FOXN1, RONU, WHN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXN1
Synonyms RONU, WHN
Function Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hematopoiesis and particularly T lineage progenitors within the bone marrow niche with age. Essential for the vascularization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively regulating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T cell ontogeny (PubMed:21507891).
Cellular Location Nucleus.
Tissue Location Expressed in thymus.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Mutations in the winged-helix transcription factor gene atthe nude locus in mice and rats produce the pleiotropic phenotypeof hairlessness and athymia, resulting in a severely compromisedimmune system. This gene is orthologous to the mouse and rat genesand encodes a similar DNA-binding transcription factor that isthought to regulate keratin gene expression. A mutation in thisgene has been correlated with T-cell immunodeficiency, the skindisorder congenital alopecia, and nail dystrophy. Alternativesplicing in the 5' UTR of this gene has been observed. [provided byRefSeq].


Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Mandinova, A., et al. J. Clin. Invest. 119(10):3127-3137(2009)Pignata, C., et al. Adv. Exp. Med. Biol. 665, 195-206 (2009) :Weiner, L., et al. Cell 130(5):932-942(2007)Nonaka, D., et al. Am. J. Surg. Pathol. 31(7):1038-1044(2007)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP12053c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions