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TBX6 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O95947
Clone Names 71009106
Peptide ID 71009106
Additional Information
Gene ID 6911
Other Names T-box transcription factor TBX6, T-box protein 6, TBX6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX6
Function T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Tissue Location Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. Knockout studies in mice indicate thatthis gene is important for specification of paraxial mesodermstructures.


Fei, Q., et al. Spine 35(9):983-988(2010)Ghebranious, N., et al. J. Bone Miner. Res. 23(10):1576-1583(2008)Farin, H.F., et al. J. Biol. Chem. 282(35):25748-25759(2007)Papapetrou, C., et al. Genomics 55(2):238-241(1999)Yi, C.H., et al. Genomics 55(1):10-20(1999)

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$ 80.00
Cat# BP12063c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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