|Other Names||Zinc finger protein 593, Zinc finger protein T86, ZNF593|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.|
|Cellular Location||Nucleus, nucleolus|
|Tissue Location||Ubiquitous. Detected in spleen, prostate, testis, small intestine, colon and to a minor level in thymus and peripheral blood leukocytes|
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ZNF593 negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.
Hayes, P.L., et al. Protein Sci. 17(3):571-576(2008)Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)Terunuma, A., et al. Nucleic Acids Res. 25(10):1984-1990(1997)
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