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Maspin Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P36952 |
|---|---|
| Clone Names | 80821072 |
| Gene ID | 5268 |
|---|---|
| Other Names | Serpin B5, Maspin, Peptidase inhibitor 5, PI-5, SERPINB5, PI5 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SERPINB5 |
|---|---|
| Synonyms | PI5 |
| Function | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Cellular Location | Secreted, extracellular space. |
| Tissue Location | Normal mammary epithelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
References
Kim, J., et al. Tumour Biol. 31(5):471-476(2010)Juengel, E., et al. World J Urol 28(4):465-471(2010)Besgen, P., et al. J. Immunol. 184(9):5392-5402(2010)Fung, C.L., et al. Histopathology 56(3):319-330(2010)Adim, S.B., et al. World J Surg Oncol 8, 22 (2010) :
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