|Other Accession||A1XSY8, NP_000390.2, NP_001129649.1|
|Other Names||E3 SUMO-protein ligase EGR2, 632-, AT591, Early growth response protein 2, EGR-2, Zinc finger protein Krox-20, EGR2, KROX20|
|Target/Specificity||The synthetic peptide sequence is selected from aa 61-74 of HUMAN EGR2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
Kim, S.H., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (7), 1355-1360 (2010) :
Myouzen, K., et al. Hum. Mol. Genet. 19(11):2313-2320(2010)
Briani, C., et al. Muscle Nerve 41(6):888-889(2010)
Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
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