|Other Names||Kelch repeat and BTB domain-containing protein 13, KBTBD13|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.|
|Tissue Location||Expressed in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
The gene belongs to a family of genes encoding proteinscontaining a BTB domain and several kelch repeats. The BTB domainfunctions as a protein-protein interaction module, which includesan ability to self-associate or to interact with non-BTBdomain-containing proteins. The kelch motif typically occurs ingroups of five to seven repeats, and has been found in proteinswith diverse functions. Known functions of these family membersinclude transcription regulation, ion channel tetramerization andgating, protein ubiquitination or degradation, and cytoskeletonregulation. The exact function of this family member has yet to bedetermined.
Stogios, P.J., et al. Genome Biol. 6 (10), R82 (2005) :
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