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hCG_1646420 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | C9JDP6 |
|---|---|
| Clone Names | 100311134 |
| Gene ID | 644672 |
|---|---|
| Other Names | Putative claudin-25, CLDN25 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CLDN25 |
|---|---|
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
| Cellular Location | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions.
References
Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :Krause, G., et al. Biochim. Biophys. Acta 1778(3):631-645(2008)Katoh, M., et al. Int. J. Mol. Med. 11(6):683-689(2003)Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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