|Other Names||Putative claudin-25, CLDN25|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Multi-pass membrane protein|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions.
Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :Krause, G., et al. Biochim. Biophys. Acta 1778(3):631-645(2008)Katoh, M., et al. Int. J. Mol. Med. 11(6):683-689(2003)Venter, J.C., et al. Science 291(5507):1304-1351(2001)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.