|Other Names||Collagen alpha-1(XXI) chain, COL21A1, COL1AL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Cytoplasm. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle|
|Tissue Location||Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the alpha chain of type XXI collagen, amember of the FACIT collagen family (fibril-associated collagenswith interrupted helices). Type XXI collagen is localized totissues containing type I collagen so, like other members of thiscollagen family, it may serve to maintain the integrity of theextracellular matrix. An alternatively spliced transcript varianthas been described, but its full-length nature has yet to bedetermined.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Chou, M.Y., et al. Genomics 79(3):395-401(2002)Tuckwell, D. Matrix Biol. 21(1):63-66(2002)Fitzgerald, J., et al. FEBS Lett. 505(2):275-280(2001)
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