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NKD2 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q969F2
Clone Names 101008100
Peptide ID 101008100
Additional Information
Gene ID 85409
Other Names Protein naked cuticle homolog 2, Naked-2, hNkd2, NKD2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKD2
Function Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
Cellular Location Cell membrane. Cytoplasm. Cytoplasmic vesicle
Tissue Location Expressed in kidney, lung, pancreas and spleen.
Research Areas
Citations (0)

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In the mouse, Nkd is a Dishevelled (see DVL1; MIM601365)-binding protein that functions as a negative regulator ofthe Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf(see MIM 602272) signaling pathway.


Hu, T., et al. J. Biol. Chem. 285(18):13561-13568(2010)Ding, W., et al. Proc. Natl. Acad. Sci. U.S.A. 105(36):13433-13438(2008)Li, C., et al. Mol. Biol. Cell 18(8):3081-3093(2007)Adamowicz, M., et al. Genes Chromosomes Cancer 45(9):829-838(2006)Li, C., et al. Proc. Natl. Acad. Sci. U.S.A. 101(15):5571-5576(2004)

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$ 80.00
Cat# BP12158b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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