|Other Names||Sesquipedalian-1, Ses1, 27 kDa inositol polyphosphate phosphatase-interacting protein A, IPIP27A, FAM109A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.|
|Cellular Location||Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that localizes to the endosomeand interacts with the enzyme, inositol polyphosphate 5-phosphataseOCRL-1. Alternate splicing results in multiple transcript variants.
Swan, L.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(8):3511-3516(2010)
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