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SLC36A1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z2H8
Clone Names 101008262
Additional Information
Gene ID 206358
Other Names Proton-coupled amino acid transporter 1, Proton/amino acid transporter 1, hPAT1, Solute carrier family 36 member 1, SLC36A1, PAT1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC36A1 (HGNC:18761)
Function Electrogenic proton/amino acid symporter with selectivity for small apolar L-amino acids, their D-enantiomers and selected amino acid derivatives such as 4-aminobutanoate/GABA (PubMed:12809675, PubMed:12527723, PubMed:19549785). May be involved in the efflux from the lysosomal compartment of neutral amino acids resulting from proteolysis (By similarity). May play a role in specifying sites for exocytosis in neurons (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Note=In neurons, colocalizes with the exocyst complex in the axonal processes {ECO:0000250|UniProtKB:Q924A5}
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the eukaryote-specific aminoacid/auxin permease (AAAP) 1 transporter family. The encodedprotein functions as a proton-dependent, small amino acidtransporter. This gene is clustered with related family members onchromosome 5q33.1.

References

Dorn, M., et al. J. Biol. Chem. 284(33):22123-22132(2009)Dorn, M., et al. FEBS Lett. 583(10):1631-1636(2009)Metzner, L., et al. Mol. Pharm. 6(3):1006-1011(2009)Anderson, C.M., et al. J. Physiol. (Lond.) 587 (PT 4), 731-744 (2009) :Metzner, L., et al. Biochim. Biophys. Acta 1778(4):1042-1050(2008)

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$ 277.78
Cat# BP12170a
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