|Other Names||Proton-coupled amino acid transporter 1, Proton/amino acid transporter 1, hPAT1, Solute carrier family 36 member 1, SLC36A1, PAT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the eukaryote-specific aminoacid/auxin permease (AAAP) 1 transporter family. The encodedprotein functions as a proton-dependent, small amino acidtransporter. This gene is clustered with related family members onchromosome 5q33.1.
Dorn, M., et al. J. Biol. Chem. 284(33):22123-22132(2009)Dorn, M., et al. FEBS Lett. 583(10):1631-1636(2009)Metzner, L., et al. Mol. Pharm. 6(3):1006-1011(2009)Anderson, C.M., et al. J. Physiol. (Lond.) 587 (PT 4), 731-744 (2009) :Metzner, L., et al. Biochim. Biophys. Acta 1778(4):1042-1050(2008)
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