RERG Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96A58 |
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Clone Names | 101109011 |
Gene ID | 85004 |
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Other Names | Ras-related and estrogen-regulated growth inhibitor, RERG |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RERG |
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Function | Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. |
Cellular Location | Cytoplasm. |
Tissue Location | Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis |
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Provided below are standard protocols that you may find useful for product applications.
Background
RERG, a member of the RAS superfamily of GTPases, inhibitscell proliferation and tumor formation (Finlin et al., 2001 [PubMed11533059]).
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)Finlin, B.S., et al. J. Biol. Chem. 276(45):42259-42267(2001)
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