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RERG Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96A58
Clone Names 101109011
Additional Information
Gene ID 85004
Other Names Ras-related and estrogen-regulated growth inhibitor, RERG
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RERG
Function Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Cellular Location Cytoplasm.
Tissue Location Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis
Research Areas
Citations (0)
citation

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Background

RERG, a member of the RAS superfamily of GTPases, inhibitscell proliferation and tumor formation (Finlin et al., 2001 [PubMed11533059]).

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)Finlin, B.S., et al. J. Biol. Chem. 276(45):42259-42267(2001)

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$ 277.78
Cat# BP12173a
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