|Other Names||Potassium channel subfamily K member 1, Inward rectifying potassium channel protein TWIK-1, Potassium channel KCNO1, KCNK1, HOHO1, KCNO1, TWIK1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HOHO1, KCNO1, TWIK1|
|Function||Weakly inward rectifying potassium channel that contributes to the regulation of the resting membrane potential.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney (PubMed:8605869).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes one of the members of the superfamily ofpotassium channel proteins containing two pore-forming P domains.The product of this gene has not been shown to be a functionalchannel, however, it may require other non-pore-forming proteinsfor activity.
Feliciangeli, S., et al. J. Biol. Chem. 285(7):4798-4805(2010)McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Zhou, M., et al. J. Neurosci. 29(26):8551-8564(2009)Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005)Rajan, S., et al. Cell 121(1):37-47(2005)
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