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HTR3A Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P46098
Clone Names 101008311
Peptide ID 101008311
Additional Information
Gene ID 3359
Other Names 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR3A
Synonyms 5HT3R, HTR3
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
Research Areas
Citations (0)

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The product of this gene belongs to the ligand-gated ionchannel receptor superfamily. This gene encodes subunit A of thetype 3 receptor for 5-hydroxytryptamine (serotonin), a biogenichormone that functions as a neurotransmitter, a hormone, and amitogen. This receptor causes fast, depolarizing responses inneurons after activation. It appears that the heteromericcombination of A and B subunits is necessary to provide the fullfunctional features of this receptor, since either subunit aloneresults in receptors with very low conductance and responseamplitude. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.


Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gatt, J.M., et al. Depress Anxiety 27(8):752-759(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)

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$ 80.00
Cat# BP12192a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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