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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PRMT8 Antibody (C-term) Blocking Peptide   

PRMT8 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NR22
Clone Names 70411210
Peptide ID 70411210
Additional Information
Gene ID 56341
Other Names Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1219b was selected from the C-term region of human PRMT8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRMT8
Synonyms HRMT1L3, HRMT1L4
Function Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Brain-specific..
Research Areas
Citations (0)

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Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.


Lee,J., J. Biol. Chem. 280 (38), 32890-32896 (2005)

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$ 80.00
Cat# BP1219b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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