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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   p130cas Antibody (Center Y224) Blocking peptide   

p130cas Antibody (Center Y224) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P56945
Clone Names 80722071
Peptide ID 80722071
Additional Information
Gene ID 9564
Other Names Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, BCAR1, CAS, CASS1, CRKAS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCAR1
Synonyms CAS, CASS1, CRKAS
Function Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Cellular Location Cell junction, focal adhesion. Cytoplasm. Note=Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.
Tissue Location Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line
Research Areas
Citations (0)

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BCAR1, or CAS, is an Src (MIM 190090) family kinasesubstrate involved in various cellular events, including migration,survival, transformation, and invasion (Sawada et al., 2006 [PubMed17129785]).


Tai, C.J., et al. Exp. Cell Res. 316(17):2969-2981(2010)Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)Schuh, N.R., et al. J. Biol. Chem. 285(4):2309-2317(2010)Wendt, M.K., et al. J. Biol. Chem. 284(49):34145-34156(2009)Qian, X., et al. Cancer Cell 16(3):246-258(2009)

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$ 80.00
Cat# BP12200c
(40 western blots)
Availability: In Stock
Bulk Size
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