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MAFB Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9Y5Q3
Clone Names 90805062
Peptide ID 90805062
Additional Information
Gene ID 9935
Other Names Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, MAFB, KRML
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KRML
Function Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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The protein encoded by this gene is a basic leucine zipper(bZIP) transcription factor that plays an important role in theregulation of lineage-specific hematopoiesis. The encoded nuclearprotein represses ETS1-mediated transcription of erythroid-specificgenes in myeloid cells. This gene contains no introns. [provided byRefSeq].


Kim, H., et al. Nat. Immunol. 11(8):743-750(2010)Beaty, T.H., et al. Nat. Genet. 42(6):525-529(2010)Vatsveen, T.K., et al. Leuk. Res. 33(12):1670-1677(2009)Zanocco-Marani, T., et al. Exp. Cell Res. 315(11):1798-1808(2009)Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)

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$ 80.00
Cat# BP12233b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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