|Other Names||Reticulon-4 receptor, Nogo receptor, NgR, Nogo-66 receptor, RTN4R, NOGOR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
|Tissue Location||Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter)|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the receptor for reticulon 4,oligodendrocyte myelin glycoprotein and myelin-associatedglycoprotein. This receptor mediates axonal growth inhibition andmay play a role in regulating axonal regeneration and plasticity inthe adult central nervous system.
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)Raiker, S.J., et al. J. Neurosci. 30(37):12432-12445(2010)Lee, E.J., et al. Oncol. Res. 18(9):401-408(2010)Zhang, L., et al. J. Neurosci. 29(19):6348-6352(2009)Voineskos, A.N. J. Neurosci. 29(16):5045-5047(2009)
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