|Other Names||Probable G-protein coupled receptor 45, PSP24-1, PSP24-alpha, GPR45|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor. May play a role in brain function.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in brain; detected in the basal forebrain, frontal cortex, and caudate, but not in thalamus, hippocampus, or putamen|
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Provided below are standard protocols that you may find useful for product applications.
This intronless gene encodes a member of the Gprotein-coupled receptor (GPCR) family. Members of this proteinfamily contain seven putative transmembrane domains and may mediatesignaling processes to the interior of the cell via activation ofheterotrimeric G proteins. This protein may function in the centralnervous system.
Salonen, J.T., et al. Am. J. Hum. Genet. 81(2):338-345(2007)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Kawasawa, Y., et al. Biochem. Biophys. Res. Commun. 276(3):957-964(2000)Kawasawa, Y., et al. Biochem. Biophys. Res. Commun. 276(3):952-956(2000)
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