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ARHGAP15 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q53QZ3 |
|---|---|
| Clone Names | 101109050 |
| Gene ID | 55843 |
|---|---|
| Other Names | Rho GTPase-activating protein 15, ArhGAP15, Rho-type GTPase-activating protein 15, ARHGAP15 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ARHGAP15 |
|---|---|
| Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
| Tissue Location | Expressed in lung, liver and lymphoid cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RHO GTPases (see ARHA; MIM 165390) regulate diversebiologic processes, and their activity is regulated by RHOGTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al.,2003 [PubMed 12650940]).
References
Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :Rose, J. Phd, et al. Mol. Med. (2010) In press :Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :Satoh, J., et al. Neuropathol. Appl. Neurobiol. 35(1):16-35(2009)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
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