TOE1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96GM8 |
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Clone Names | 80612072 |
Gene ID | 114034 |
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Other Names | Target of EGR1 protein 1, TOE1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TOE1 |
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Function | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684). |
Cellular Location | Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TOE1 inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)De Belle, I., et al. J. Biol. Chem. 278(16):14306-14312(2003)Robertson, N.G., et al. Genomics 23(1):42-50(1994)
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