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TLE2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q04725 |
|---|---|
| Clone Names | 80924252 |
| Gene ID | 7089 |
|---|---|
| Other Names | Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TLE2 |
|---|---|
| Function | Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | In all tissues examined, mostly in heart, brain, and muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
References
He, Z., et al. J. Virol. 84(4):2047-2062(2010)Arce, L., et al. BMC Cancer 9, 159 (2009) :Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :Grbavec, D., et al. Biochem. J. 337 (PT 1), 13-17 (1999) :
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