|Other Names||Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane|
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Provided below are standard protocols that you may find useful for product applications.
GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :Saus, E., et al. J Psychiatr Res (2010) In press :Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)Niemann, S., et al. Neurology 70(9):666-676(2008)
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