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KCNJ8 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15842
Clone Names 100318046
Additional Information
Gene ID 3764
Other Names ATP-sensitive inward rectifier potassium channel 8, Inward rectifier K(+) channel Kir61, Potassium channel, inwardly rectifying subfamily J member 8, uKATP-1, KCNJ8
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ8
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Predominantly detected in fetal and adult heart.
Research Areas
Citations (0)
citation

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Background

Potassium channels are present in most mammalian cells,where they participate in a wide range of physiologic responses.The protein encoded by this gene is an integral membrane proteinand inward-rectifier type potassium channel. The encoded protein,which has a greater tendency to allow potassium to flow into a cellrather than out of a cell, is controlled by G-proteins. [providedby RefSeq].

References

Medeiros-Domingo, A., et al. Heart Rhythm 7(10):1466-1471(2010)Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)Shi, W., et al. J. Biol. Chem. 285(5):3021-3029(2010)Winkler, M., et al. J. Biol. Chem. 284(11):6752-6762(2009)Ploug, K.B., et al. Eur. J. Pharmacol. 601 (1-3), 43-49 (2008) :

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$ 277.78
Cat# BP12302a
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