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IL1F5 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UBH0
Clone Names 100318050
Peptide ID 100318050
Additional Information
Gene ID 26525
Other Names Interleukin-36 receptor antagonist protein, IL-36Ra, FIL1 delta, IL-1-related protein 3, IL-1RP3, Interleukin-1 HY1, IL-1HY1, Interleukin-1 delta, IL-1 delta, Interleukin-1 family member 5, IL-1F5, Interleukin-1 receptor antagonist homolog 1, IL-1ra homolog 1, Interleukin-1-like protein 1, IL-1L1, IL36RN, FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL36RN
Synonyms FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3
Function Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
Cellular Location Secreted.
Tissue Location Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Detected also in the spleen, brain leukocyte and macrophage cell types Increased in lesional psoriasis skin
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theinterleukin 1 cytokine family. This cytokine was shown tospecifically inhibit the activation of NF-kappaB induced byinterleukin 1 family, member 6 (IL1F6). This gene and eight otherinterleukin 1 family genes form a cytokine gene cluster onchromosome 2. Two alternatively spliced transcript variantsencoding the same protein have been reported.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Jung, M.Y., et al. Scand. J. Rheumatol. 39(3):190-196(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP12304a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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