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SFRS7 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q16629
Clone Names 100318053
Peptide ID 100318053
Additional Information
Gene ID 6432
Other Names Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRSF7
Synonyms SFRS7
Function Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
Cellular Location Nucleus. Cytoplasm
Tissue Location Brain, liver, kidney and lung.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theserine/arginine (SR)-rich family of pre-mRNA splicing factors,which constitute part of the spliceosome. Each of these factorscontains an RNA recognition motif (RRM) for binding RNA and an RSdomain for binding other proteins. The RS domain is rich in serineand arginine residues and facilitates interaction between differentSR splicing factors. In addition to being critical for mRNAsplicing, the SR proteins have also been shown to be involved inmRNA export from the nucleus and in translation. Two transcriptvariants encoding different isoforms have been found for this gene.


Kimura, T., et al. Med Mol Morphol 43(3):145-157(2010)Escudero-Paunetto, L., et al. Virology 401(2):155-164(2010)Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)Valente, S.T., et al. Mol. Cell 36(2):279-289(2009)Shepard, P.J., et al. Genome Biol. 10 (10), 242 (2009) :

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$ 80.00
Cat# BP12306a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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