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CALU Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43852 |
|---|---|
| Clone Names | 100318064 |
| Gene ID | 813 |
|---|---|
| Other Names | Calumenin, Crocalbin, IEF SSP 9302, CALU |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CALU |
|---|---|
| Function | Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma- carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Tissue Location | Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene is a calcium-binding proteinlocalized in the endoplasmic reticulum (ER) and it is involved insuch ER functions as protein folding and sorting. This proteinbelongs to a family of multiple EF-hand proteins (CERC) thatinclude reticulocalbin, ERC-55, and Cab45 and the product of thisgene. Alternatively spliced transcript variants encoding differentisoforms have been identified.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Carlquist, J.F., et al. J. Thromb. Thrombolysis 30(3):358-364(2010)Hernandez-Romero, D., et al. Ann. Med. 42(6):439-446(2010)Harada, T., et al. Thromb. Res. 126(3):183-190(2010)Voora, D., et al. Clin. Pharmacol. Ther. 87(4):445-451(2010)
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