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PDCD1LG2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BQ51
Clone Names 100318076
Peptide ID 100318076
Additional Information
Gene ID 80380
Other Names Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCD1LG2
Synonyms B7DC, CD273, PDCD1L2, PDL2
Function Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Cellular Location Isoform 3: Secreted Isoform 1: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161}
Tissue Location Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Research Areas
Citations (0)

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Background

PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).

References

Ellis, J.S., et al. J. Immunol. 185(6):3149-3157(2010)Pena-Cruz, V., et al. J. Invest. Dermatol. 130(9):2222-2230(2010)Ghiotto, M., et al. Int. Immunol. 22(8):651-660(2010)Ishizaki, Y., et al. Hum. Genet. (2010) In press :Kassel, R., et al. Hepatology 50(5):1625-1637(2009)

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$ 80.00
Cat# BP12309a
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