|Other Names||Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.|
|Tissue Location||Expressed only in a subset of type 2 skeletal muscle fibers.|
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Alpha-actinin is an actin-binding protein with multipleroles in different cell types. This gene expression is limited toskeletal muscle. It is localized to the Z-disc and analogous densebodies, where it helps to anchor the myofibrillar actin filaments
Rodriguez-Romo, G., et al. Eur. J. Appl. Physiol. 110(6):1099-1106(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Berman, Y., et al. Physiology (Bethesda) 25(4):250-259(2010)Ruiz, J.R., et al. Scand J Med Sci Sports (2010) In press :Buxens, A., et al. Scand J Med Sci Sports (2010) In press :
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