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RALBP1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15311
Clone Names 101008019
Peptide ID 101008019
Additional Information
Gene ID 10928
Other Names RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RLIP1, RLIP76
Function Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Cellular Location Membrane; Peripheral membrane protein
Tissue Location Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes
Research Areas
Citations (0)

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RALBP1 plays a role in receptor-mediated endocytosis andis a downstream effector of the small GTP-binding protein RAL (seeRALA; MIM 179550). Small G proteins, such as RAL, have GDP-boundinactive and GTP-bound active forms, which shift from the inactiveto the active state through the action of RALGDS (MIM 601619),which in turn is activated by RAS (see HRAS; MIM 190020) (summaryby Feig, 2003 [PubMed 12888294]).


Singhal, S.S., et al. Int. J. Cancer 126(6):1327-1338(2010)Singhal, S.S., et al. Cancer Lett. 283(2):152-158(2009)Awasthi, Y.C., et al. J Toxicol Environ Health B Crit Rev 12(7):540-551(2009)Singhal, S.S., et al. Cancer Res. 69(10):4244-4251(2009)Singhal, S.S., et al. Biochem. Pharmacol. 77(6):1074-1083(2009)

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$ 80.00
Cat# BP12329c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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