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SENP2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HC62
Clone Names 2020505
Peptide ID 2020505
Additional Information
Gene ID 59343
Other Names Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1232c was selected from the C-term region of human SENP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SENP2
Synonyms KIAA1331
Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1.
Cellular Location Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side Cytoplasm. Note=Shuttles between cytoplasm and nucleus
Research Areas
Citations (0)

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SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.


Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).Nakajima, D., et al., DNA Res. 9(3):99-106 (2002).Zhang, H., et al., Mol. Cell. Biol. 22(18):6498-6508 (2002).Hang, J., et al., J. Biol. Chem. 277(22):19961-19966 (2002).Nagase, T., et al., DNA Res. 7(1):65-73 (2000).

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$ 80.00
Cat# BP1232c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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