MDM1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TC05 |
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Clone Names | 91208283 |
Gene ID | 56890 |
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Other Names | Nuclear protein MDM1, MDM1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MDM1 |
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Function | Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules (PubMed:26337392). |
Cellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the centriole lumen |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a nuclear protein similar to the mousedouble minute 1 protein. The mouse gene is located in double minute(DM) chromatin particles and is amplified in the mouse transformed3T3 cell line, and the protein is able to bind to p53. In mouseseveral transcripts have been described for this gene which resultfrom alternative polyadenylation, splicing and exon usage.
References
Chang, B., et al. Hum. Mol. Genet. 17(24):3929-3941(2008)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Snyder, L.C., et al. J. Biol. Chem. 263(32):17150-17158(1988)
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