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JHDM2a Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9Y4C1
Clone Names 71130178
Peptide ID 71130178
Additional Information
Gene ID 55818
Other Names Lysine-specific demethylase 3A, 11411-, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A, KDM3A, JHDM2A, JMJD1, JMJD1A, KIAA0742, TSGA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KDM3A
Synonyms JHDM2A, JMJD1, JMJD1A, KIAA0742, TSGA
Function Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
Cellular Location Cytoplasm. Nucleus. Note=Nuclear in round spermatids. When spermatids start to elongate, localizes to the cytoplasm where it forms distinct foci which disappear in mature spermatozoa (By similarity).
Research Areas
Citations (0)

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KDM3A is a zinc finger protein that contains ajumonji domain and may play a role in hormone-dependenttranscriptional activation.


Suikki, H.E., et al. Prostate 70(8):889-898(2010)Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)Chen, H., et al. J. Biol. Chem. 285(10):7374-7383(2010)Krieg, A.J., et al. Mol. Cell. Biol. 30(1):344-353(2010)Sar, A., et al. Cell Tissue Res. 337(2):223-234(2009)

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$ 80.00
Cat# BP12346b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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