|Other Names||Carbohydrate sulfotransferase 6, 282-, Corneal N-acetylglucosamine-6-O-sulfotransferase, C-GlcNAc6ST, hCGn6ST, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta, GST4-beta, N-acetylglucosamine 6-O-sulfotransferase 5, GlcNAc6ST-5, Gn6st-5, CHST6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N- acetyllactosamine structures.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is an enzyme thatcatalyzes the transfer of a sulfate group to the GlcNAc residues ofkeratan. Keratan sulfate helps maintain corneal transparency.Defects in this gene are a cause of macular corneal dystrophy(MCD).
Liu, Z., et al. Cornea 29(8):883-888(2010)Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)Dang, X., et al. Mol. Vis. 15, 700-705 (2009) :Birgani, S.A., et al. Mol. Vis. 15, 373-377 (2009) :Sultana, A., et al. Mol. Vis. 15, 319-325 (2009) :
If you have any additional inquiries please email technical services at firstname.lastname@example.org.