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SFRP2 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96HF1
Clone Names 100311243
Additional Information
Gene ID 6423
Other Names Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SFRP2
Synonyms FRP2, SARP1
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Cellular Location Secreted.
Tissue Location Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the SFRP family thatcontains a cysteine-rich domain homologous to the putativeWnt-binding site of Frizzled proteins. SFRPs act as solublemodulators of Wnt signaling. Methylation of this gene is apotential marker for the presence of colorectal cancer. [providedby RefSeq].

References

von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400(3):299-304(2010)Pehlivan, S., et al. Cancer Genet. Cytogenet. 201(2):128-132(2010)Kohno, H., et al. Oncol. Rep. 24(2):423-431(2010)Yamamura, S., et al. Mol. Cancer Ther. 9(6):1680-1687(2010)Forsman, H., et al. BMC Cell Biol. 11, 52 (2010) :

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$ 277.78
Cat# BP12351b
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