|Other Names||60S ribosomal protein L11, CLL-associated antigen KW-12, RPL11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity).|
|Cellular Location||Nucleus, nucleolus.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L5P family of ribosomal proteins. It is located in thecytoplasm. The protein probably associates with the 5S rRNA.Alternative splice variants encoding different isoforms may exist,but they have not been fully characterized. As is typical for genesencoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. [provided byRefSeq].
Sun, X.X., et al. J. Biol. Chem. 285(33):25812-25821(2010)Konno, Y., et al. Haematologica 95(8):1293-1299(2010)Dai, M.S., et al. J. Biol. Chem. 285(17):12587-12594(2010)Holzel, M., et al. J. Biol. Chem. 285(9):6364-6370(2010)Quarello, P., et al. Haematologica 95(2):206-213(2010)
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