|Other Names||Cytoskeleton-associated protein 4, 63-kDa cytoskeleton-linking membrane protein, Climp-63, p63, CKAP4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||High-affinity epithelial cell surface receptor for APF.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Translocates to the perinuclear region upon APF- stimulation|
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Provided below are standard protocols that you may find useful for product applications.
CKAP4 is a substrate of DHHC2, a putative tumor suppressor. CK MNF116 and CKAP4 were useful in identifying squamous cell carcinomas with single cell infiltration. These results suggest a role for CKAP4 in tumor.
Kanner, W.A., et al. J. Cutan. Pathol. 37(7):744-750(2010)Tomkova, H., et al. Eur J Dermatol 20(3):411-413(2010)Lefkimmiatis, K., et al. Cancer Res. 69(22):8563-8571(2009)Planey, S.L., et al. Mol. Biol. Cell 20(5):1454-1463(2009)Bates, S.R., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (4), L658-L669 (2008) :
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