SNRPB2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P08579 |
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Clone Names | 100318196 |
Gene ID | 6629 |
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Other Names | U2 small nuclear ribonucleoprotein B'', U2 snRNP B'', SNRPB2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SNRPB2 |
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Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346, PubMed:32494006). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128, PubMed:32494006). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene associates with stem loopIV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presenceof snRNP-A'. The encoded protein may play a role in pre-mRNAsplicing. Autoantibodies from patients with systemic lupuserythematosus frequently recognize epitopes on the encoded protein.Two transcript variants encoding the same protein have been foundfor this gene.
References
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Chung, S., et al. Biochim. Biophys. Acta 1576(3):287-297(2002)Jurica, M.S., et al. RNA 8(4):426-439(2002)
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