|Other Names||U2 small nuclear ribonucleoprotein B'', U2 snRNP B'', SNRPB2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the U2A' protein.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene associates with stem loopIV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presenceof snRNP-A'. The encoded protein may play a role in pre-mRNAsplicing. Autoantibodies from patients with systemic lupuserythematosus frequently recognize epitopes on the encoded protein.Two transcript variants encoding the same protein have been foundfor this gene.
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Chung, S., et al. Biochim. Biophys. Acta 1576(3):287-297(2002)Jurica, M.S., et al. RNA 8(4):426-439(2002)
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