|Other Names||Sodium- and chloride-dependent glycine transporter 1, GlyT-1, GlyT1, Solute carrier family 6 member 9, SLC6A9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain|
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Provided below are standard protocols that you may find useful for product applications.
SLC6A9 terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Koller, G., et al. Addict Biol 14(4):506-508(2009)Liu, X., et al. Biochem. Biophys. Res. Commun. 384(4):530-534(2009)Ueno, T., et al. J. Atheroscler. Thromb. 16(3):201-206(2009)Deng, X., et al. BMC Psychiatry 8, 58 (2008) :
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