|Other Names||Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 member 6, SLC6A6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.|
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Provided below are standard protocols that you may find useful for product applications.
SLC6A6 is required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake.
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Askwith, T., et al. Am. J. Physiol. Endocrinol. Metab. 297 (3), E620-E628 (2009) :Han, X., et al. J. Am. Soc. Nephrol. 20(6):1323-1332(2009)Anderson, C.M., et al. J. Physiol. (Lond.) 587 (PT 4), 731-744 (2009) :
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