|Other Names||Delta-like protein 3, Drosophila Delta homolog 3, Delta3, DLL3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the delta protein ligandfamily. This family functions as Notch ligands that arecharacterized by a DSL domain, EGF repeats, and a transmembranedomain. Mutations in this gene cause autosomal recessivespondylocostal dysostosis 1. Two transcript variants encodingdistinct isoforms have been identified for this gene. [provided byRefSeq].
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Heuss, S.F., et al. Proc. Natl. Acad. Sci. U.S.A. 105(32):11212-11217(2008)Maisenbacher, M.K., et al. Hum. Genet. 116(5):416-419(2005)Whittock, N.V., et al. Clin. Genet. 66(1):67-72(2004)Bonafe, L., et al. Clin. Genet. 64(1):28-35(2003)
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