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SET1B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UPS6
Clone Names 71130140
Peptide ID 71130140
Additional Information
Gene ID 23067
Other Names Histone-lysine N-methyltransferase SETD1B, Lysine N-methyltransferase 2G, SET domain-containing protein 1B, hSET1B, SETD1B, KIAA1076, KMT2G, SET1B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1076, KMT2G, SET1B
Function Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys- 9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Cellular Location Nucleus speckle. Chromosome. Note=Localizes to a largely non- overlapping set of euchromatic nuclear speckles with SETD1A, suggesting that SETD1A and SET1B each bind to a unique set of target genes
Research Areas
Citations (0)

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SET1B is a component of a histone methyltransferasecomplex that produces trimethylated histone H3 at Lys4 (Lee et al.,2007 [PubMed 17355966]).


Wu, M., et al. Mol. Cell. Biol. 28(24):7337-7344(2008)Lee, J.H., et al. Mol. Cell. Biol. 28(2):609-618(2008)Lee, J.H., et al. J. Biol. Chem. 282(18):13419-13428(2007)

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$ 80.00
Cat# BP12413b
(40 western blots)
Availability: In Stock
Bulk Size
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