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EIF2B1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q14232
Clone Names 80703063
Peptide ID 80703063
Additional Information
Gene ID 1967
Other Names Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha, EIF2B1, EIF2BA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EIF2B1
Synonyms EIF2BA
Function Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Research Areas
Citations (0)

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Background

This gene encodes one of five subunits of eukaryotictranslation initiation factor 2B (EIF2B), a GTP exchange factor foreukaryotic initiation factor 2 and an essential regulator forprotein synthesis. Mutations in this gene and the genes encodingother EIF2B subunits have been associated with leukoencephalopathywith vanishing white matter.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Hiyama, T.B., et al. J. Mol. Biol. 392(4):937-951(2009)Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)van der Knaap, M.S., et al. Neuropediatrics 38 (5), 264 (2007) :

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$ 80.00
Cat# BP12415c
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