|Other Names||Calponin-2, Calponin H2, smooth muscle, Neutral calponin, CNN2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.|
|Tissue Location||Heart and smooth muscle.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene, which can bind actin,calmodulin, troponin C, and tropomyosin, may function in thestructural organization of actin filaments. The encoded proteincould play a role in smooth muscle contraction and cell adhesion.Two transcript variants encoding different isoforms have been foundfor this gene.
Rikova, K., et al. Cell 131(6):1190-1203(2007)Hossain, M.M., et al. J. Biol. Chem. 280(51):42442-42453(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)Hossain, M.M., et al. Am. J. Physiol., Cell Physiol. 284 (1), C156-C167 (2003) :
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