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CL052 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96K30
Other Accession NP_116237.1
Clone Names 91208249
Additional Information
Gene ID 84934
Other Names RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA1, C12orf52, RITA
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RITA1
Synonyms C12orf52, RITA
Function Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Cellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear
Research Areas
Citations (0)
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References

Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 277.78
Cat# BP12423a
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