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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SLC22A8 Antibody (C-term) Blocking peptide   

SLC22A8 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TCC7
Clone Names 101008170
Peptide ID 101008170
Additional Information
Gene ID 9376
Other Names Solute carrier family 22 member 8, Organic anion transporter 3, hOAT3, SLC22A8, OAT3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC22A8
Synonyms OAT3
Function Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Cellular Location Basolateral cell membrane; Multi-pass membrane protein. Note=Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity)
Tissue Location Expressed in kidney.
Research Areas
Citations (0)

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Background

This gene encodes a protein involved in thesodium-independent transport and excretion of organic anions, someof which are potentially toxic. The encoded protein is an integralmembrane protein and appears to be localized to the basolateralmembrane of the kidney. Multiple alternatively spliced transcriptvariants that encode different protein isoforms have been describedfor this gene.

References

Duan, P., et al. Eur. J. Pharmacol. 627 (1-3), 49-55 (2010) :Rodiger, M., et al. Can. J. Physiol. Pharmacol. 88(2):141-146(2010)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Holmes, M.V., et al. PLoS ONE 4 (12), E7960 (2009) :Torres, A.M. World J. Gastroenterol. 14(43):6616-6621(2008)

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$ 80.00
Cat# BP12434b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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